Carglumic acid

Carglumic Acid

Carglumic acid is an analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency.

Systematic Name

(2S)-2-(carbamoylamino)pentanedioic acid

Therapeutic Category

Hyperammonemia

Suitable Formulations

Solid

Approvals

US DMF*, EU ASMF

EU-WC

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